(949) 996-5355
Book an Appointment
(949) 996-5355
Book an Appointment
  • Advanced Neuromodulation

VNSTherapy

in Newport Beach & San Juan Capistrano, CA
Vagus Nerve Stimulation using the LivaNova Symmetry™ System—an FDA-cleared, implantable neuromodulation therapy for treatment-resistant depression and epilepsy.
Schedule a Consultation
Our Approach
  • Understanding VNS

What is VNS Therapy?

Vagus Nerve Stimulation (VNS) Therapy uses an implanted device to send mild electrical pulses through the vagus nerve to the brain. The LivaNova Symmetry™ System represents the latest generation of VNS technology, offering improved outcomes for patients with treatment-resistant depression who have not responded to medication, therapy, or other interventions. At Resiliency, we evaluate candidates for VNS and provide ongoing management and optimization of the device.

FDA-cleared for treatment-resistant depression

LivaNova Symmetry™ System technology

Complementary to other treatments (Deep TMS, medication)

FDA

Cleared Device

  • The Science

How VNS Therapy Works

Understanding the three key principles behind Vagus Nerve Stimulation therapy.

Vagus Nerve Stimulation

A small pulse generator implanted under the skin sends regular electrical impulses through the vagus nerve to mood-regulating brain regions.

Neural Modulation

These pulses help regulate neurotransmitter systems including serotonin, norepinephrine, and GABA that are disrupted in depression.

Progressive Improvement

Benefits typically build gradually over months as the brain's neural circuits are progressively modulated.

  • The Vagus Nerve

What is the Vagus Nerve?

The vagus nerve is the longest cranial nerve in the body, running from the brain all the way to the large intestine. It plays a critical role in regulating many of the body’s most important functions.

Mood regulation

Heart rate & blood pressure

Immune responses

Speech & taste

Digestion

Respiration

Sensory perception

Mucus & saliva production

  • Your Journey

How It Works

Getting started with telehealth is simple and straightforward.

01

Evaluation & Candidacy

Our team conducts a thorough psychiatric evaluation to determine if VNS is appropriate based on your treatment history, diagnosis, and overall health. We manage insurance prior authorization, which typically requires a 6-month process handled by the manufacturer.

02

Outpatient Implantation

The device is surgically implanted during an outpatient procedure lasting 1-2 hours under general anesthesia. A pacemaker-like pulse generator is placed under the skin below the left collarbone, connected to a wire along the vagus nerve. Same-day discharge is typical.

03

Programming & Ongoing Care

Programming and pulse adjustments are performed in-office and are quick and painless. Your physician adjusts the electrical pulse frequency and duration for optimal results. VNS is an adjunctive long-term treatment—you continue your existing therapies alongside it.

  • Candidacy

Who Is a Candidate?

VNS Therapy may be appropriate for patients who meet the following criteria.

Treatment-Resistant Depression

Patients with treatment-resistant depression who have failed multiple medications.

Beyond Deep TMS & Spravato

Those who have tried Deep TMS and/or Spravato without adequate response.

Comorbid Epilepsy

Patients with comorbid epilepsy and depression.

Long-Term Solution

Individuals seeking a long-term, implantable solution.

  • Common Questions

Frequently Asked Questions

How is VNS different from Deep TMS?
Deep TMS is non-invasive and delivered in daily clinic sessions. VNS requires a minor surgical procedure to implant a device that then delivers continuous therapy 24/7. VNS is typically considered after Deep TMS and other non-invasive options have been tried.
VNS is covered by many insurance plans and Medicare. Prior authorization typically requires approximately 6 months and is managed by the device manufacturer. Our team assists with benefits verification throughout the process.
The most common side effects include temporary hoarseness, cough, shortness of breath, and throat discomfort during stimulation. These are generally mild and well-tolerated, often decreasing over time.
The device is implanted during outpatient hospital surgery lasting 1-2 hours under general anesthesia, with same-day discharge typical. The lead wire remains invisible, and the neurostimulator (approximately 2 inches in diameter) is positioned below the left collarbone. It may be slightly visible on smaller frames.
Yes. VNS is an add-on treatment designed to complement your existing care. Most patients continue their antidepressant medications and other therapies alongside VNS for the best outcomes.

Have more questions? Contact our clinical team.

Learn If VNS Is Right For You

Schedule a consultation with our team to discuss whether VNS Therapy could be the next step in your treatment journey.
Schedule Your Consultation
(949) 996-5355
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